The actions of C-peptide in HEK293 cells are dependent upon insulin and extracellular glucose concentrations

Peptides(2022)

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摘要
•C-peptide increases cFos mRNA expression in HEK293 cells via an interaction with GPR146.•C-peptide-induced cFos mRNA expression is reduced by co-treatment with insulin.•C-peptide-induced cFos mRNA expression is dependent upon extracellular glucose concentration.
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关键词
C-peptide,Insulin,GPR146,Insulin receptor,Extracellular glucose concentration
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