Simultaneous or staged resection of synchronous colorectal cancer liver metastases: a 13-year institutional follow-up

Background: This study compared postoperative outcomes and survival rates of patients who un-derwent simultaneous or staged resection for synchronous colorectal cancer liver metastases. Methods: Between 2005 and 2018, 126 patients were registered prospectively at a university hospital in Sweden, 63 patients who underwent simultaneous resection were matched against 63 patients who underwent staged resection.Results: The length of hospital stay was shorter for the simultaneous resection group, at 11 vs 16 days, p = <0.001. Fewer patients experienced recurrence in the simultaneous resection group 39 vs 50 pa-tients, p = 0.012. There were no significant differences in disease-free survival and overall survival be-tween the groups. Age (hazard ratio [HR] 1.72; 95% CI 1.01-2.94; p = 0.049) and Clavien-Dindo score (HR 2.22; 95% CI 1.06-4.67; p = 0.035) had impact on survival. Conclusion: Colorectal cancer with synchronous liver metastases can be resected simultaneously, and enables a shorter treatment time without jeopardizing oncological outcomes.