Abreu Enrichment Mediates Rhinosinusitis tuberculostearicum Corynebacterium Sinus Microbiome Diversity Depletion and

semanticscholar(2012)

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摘要
may serve as a new therapeutic for CRS. L. sakei humans, induced sinusitis, even when the microbiome was depleted. If these effects are consistent in − tuberculostearicum C. was sufficient to protect against Lactobacillus sakei sinusitis in the absence of a normal microbiota. Moreover, contributed to the development of C. tuberculostearicum . In a murine model, Corynebacterium tuberculostearicum reduced bacterial diversity in the CRS patients, with specific depletion of lactic acid bacteria and a relative increase in The authors performed comparative microbiome profiling of patients with CRS and healthy controls. They found pathogenic species. prevalent in CRS patients than in healthy controls as well as a bacterial candidate that may protect against this identify both a potential pathogenic species that is more et al. microbiota to CRS remains unclear. Now, Abreu microbial infection, which can be expected to perturb the mucosal microbiota; however, the contribution of sinus than 12 weeks, affects more than 30 million Americans. CRS is characterized by persistent mucosal inflammation and affects an individual's quality of life. Indeed, chronic rhinosinusitis (CRS), which is defined as sinusitis lasting longer If the frequency of ads for sinus-clearing drugs tells us anything, sinusitis is a widespread problem that directly Nosing in on Chronic Sinusitis
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