Comprehensive and Routine Characterization of Proteins and Peptides using an Integrated Waters LC-MS Workflow and LC -MSE : Waters

This application note focuses on intact protein measurement and peptide mapping for biotherapeutics. We demonstrate a Waters system solution and workflow that integrates ACQUITY UPLC separations, application-specific column chemistries, Xevo QTof MS mass detection, and industry-leading biopharmaceutical informatics to deliver improvements in laboratory productivity. Tasks that took two weeks to complete, such as peptide mapping, can now be accomplished in a day.