An ultrapulsed CO2 laser combined with a long-pulsed Nd:YAG laser for the treatment of oral and maxillofacial pyogenic granuloma

Background: Pyogenic granuloma is a common, benign, acquired vascular lesion involving the skin and mucous membrane. It occurs in exposed areas, such as oral and maxillofacial regions, hands and feet, which usually have aesthetic affections on the patients’ appearance. Although pyogenic granuloma is treatable by a variety of treatments, they bear defects such as high recurrence rate, multiple therapies, leaving obvious scars, hyperpigmentation, or skin atrophy. In this study, we treat pyogenic granuloma patients with both ultrapulsed CO2 laser and long-pulsed Nd: YAG laser, in order to achieve ideal effects. Methods: 20 participants with pyogenic granuloma of the oral and maxillofacial region were treated with ultrapulsed CO2 laser and long-pulsed Nd: YAG laser, reexamined one month later, and followed up for one year. Clinical characteristics and treatment effects were recorded and examined.Results: The 20 participants were all cured by one treatment with a cure rate of 100%. None of the patients had scar or recurrence during12 months of follow-up. Conclusions: Ultrapulsed CO2 laser combined with long-pulsed Nd: YAG laser is a safe and cosmetically effective solution for pyogenic granuloma of the oral and maxillofacial region.Trial registration: This research is a retrospective study.