Clinical and Immunological Assessment of Renal Transplant Recipients

Rita Mônica Borges Studart, Amanda Câmara Nunes, Renata Moura de Queiroz, Lise Maria Pinheiro de,Mattos Brito,Isabela Melo Bonfim, Karla Soares de Castro

semanticscholar(2019)

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摘要
Objective: The study’s purpose has been to assess both clinical and immunological characteristics of renal transplant recipients. Methods: It is a documentary and retrospective study that was performed at the renal transplantation ambulatory from the Hospital Geral de Fortaleza (HGF), Fortaleza city, Ceará State, with patients hospitalized from June 2012 to June 2014. The sample consisted of 300 patients submitted to renal transplantation. The predictive variables of interest were subdivided in the following categories: pre-transplant characteristics, post-transplant characteristics and immunological characteristics. Pearson and Spearman tests were used to evaluate the correlation between variables. Results: There was a predominance of male patients (65%), with ages ranging from 44 to 56 years (31.4%). A statistically significant relationship was found between the Donor-Specific Antibody and Delayed Graft Function (p<0.04), Cellular Rejection and PanelReactive Antibody class I (p<0.05), duration of hospitalization and Delayed Graft Function (p<0.001) and also between the Human Leukocyte Antigen and MISMATCH. Conclusion: It is pointed out the need for a critical and individualized follow-up of the transplanted patient by the professionals to guarantee the long-term transplantation success. Descriptors: Assessment, kidney transplantation, Nursing. 1 Nursing Graduate by the UNIFOR, PhD in Nursing by the Universidade Federal do Ceará (UFC), Professor at UNIFOR. Universidade de Fortaleza (UNIFOR), Brazil. 2 Nursing Graduate by the UNIFOR, Postgraduate in Organ transplantation by the Universidade Estadual do Ceará (UECE), Residency student in Diabetes Care by the UFC. Hospital Universitário Walter Cantídio, Brazil. 3 Nursing Graduate by the UNIFOR, Analyst Nurse who works supporting health and hospital management. Universidade de Fortaleza (UNIFOR), Brazil. 4 Nursing Graduate by the UECE, Specialist’s Degree in Hospital Infection Control by the UFC, MSc in Nursing Technology and Innovation by the UNIFOR, Registered Nurse at Hospital Universitário Walter Cantídio. Hospital Universitário Walter Cantídio, Brazil. 5 Nursing Graduate by the UFC, Specialist’s Degree in Nephrology by the UECE, PhD in Nursing by the UFC, Professor of the Nursing Graduation Course at UNIFOR. Universidade de Fortaleza (UNIFOR), Brazil. 6 Nursing Graduate by the UNIFOR, Specialist’s Degree in Nephrology by the UECE, MSc in Nursing Technology and Innovation by the UNIFOR, Registered Nurse at HGF. Hospital Geral de Fortaleza (HGF), Brazil.
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