Production of Collagen Nanofibers and Unfolding of the Structure

In this paper, we discuss two different collagen nanofiber production methods, namely, electrospinning and self-assembly of collagen fibers. The robustness and advantages of the methods are discussed. Scanning Electron Microscopy (SEM), Circular Dichroism (CD), Differential Scanning Calorimetry (DSC) methods are applied to compare the collagen fibrillary structures that are obtained by these techniques. The possible effects of applied methods and processes on the native structure are discussed and the future direction of the research is presented.