Selective Modulation of Monocyte and Neutrophil Responses with Activated Protein C in Preterm Infants

Hassan Eliwan,R William Watson,Ashanty Melo, Murwan Omer,Ali Jafar,Fiona O Hare,Paul Downey,Eoghan E Mooney,Amanda O Neill,Alfonso Blanco,Brian Philbin,Michelle O Rourke,irene Regan,Beatrice Nolan,Owen Smith,Eleanor Molloy

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians（2020）

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摘要

Increased systemic ROI release in preterm infants may mediate tissue damage, ROI was reduced by APC. However, due to the high risk of hemorrhage further examination of APC mutant forms with anti-inflammatory but decreased anticoagulant properties is merited.

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关键词

Neutrophil,activated protein C,monocyte,preterm infant,toll-like receptor 4

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