Humanized three-dimensional scaffold xenotransplantation models for myelodysplastic syndromes
Experimental Hematology（2022）
摘要
•Humanized 3-D scaffolds improve engraftment of MDS patient samples into NSG mice.•Human bone marrow niche cells can be maintained long term in xenotransplanted ossicles.•Ossicle methods are easier to handle manually during transplantation.
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