A review on oral fast dissolving films a novel drug delivery system-1

INTRODUCTON Fast dissolving drug-delivery systems were first developed in 1970s as an alternative to tablets, capsules, and syrups for pediatric and geriatric patients for experienced difficulties in swallowing traditional oral solid-dosage forms.OFDF is one of such novel approach to increase consumer acceptance by vitu of rapid dissolution, selfadministration, easy to handle, convenient packaging, alleviates and pleasant taste. Oral fast dissolving film (OFDF) is also known as mouth dissolving film (MDF), oral strips, Oro-dispersive ABSTRACT Oral route is most common and convenient route for the administration of drug because of the low cost of therapy and ease of administration lead to high levels of p atient compliance as in the form of tablets and cap sules. In some cases, the oral solid dosage form may become d ifficult especially in swallowing (egs: motion sick ness, sudden episode of allergic reaction, coughing, fear of choking, unavailability of water, and in differ ent age group of patient and patients who suffer from dysphagia). To overcome these difficulties, fast dissolving dr ug delivery systems have been developed Fast dissolving oral de livery systems are solid dosage forms, which disint egrate or dissolve within 1 min when placed in the mouth with out water or chewing. These thin sized film stripes are designed in such a manner for ease administration o f drug when its placed on or under the tongue. Ther e by the film enables the drug to deliver directly in to the blood stream either buccally or sublingually. Like wise, to improves the onset of action, lower the dosing and e hance the efficacy.