Bigels as drug delivery systems: From their components to their applications

Drug Discovery Today(2022)

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摘要
•Bigels are systems that usually result from mixing a hydrogel and an organogel.•A hydrophilic biopolymer is commonly the structuring agent of the aqueous phase.•An organogelator causes the vegetable oil to be gelled forming the organogel.•Factors like organogel/hydrogel ratio condition bigels features and drug release.•Bigels for transdermal, buccal and vaginal drug delivery have been developed.
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关键词
Hydrogel,Organogel,Organogelator,Bigel manufacturing,Bigel characterization,Drug delivery bigels
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