Vascular inflammation and impaired reverse cholesterol transport and lipid metabolism in obese children and adolescents

Maximiliano Martin,Laura Gaete,Walter Tetzlaff,Florencia Ferraro,Ezequiel Lozano Chiappe,Eliana E. Botta,Viviana Osta,Maria S. Saez,Maria V. Lorenzon Gonzalez, Patricia Palenque,Gabriela Ballerini,Patricia Sorroche,Laura Boero, Liliana Triffone,Fernando Brites

Nutrition, Metabolism and Cardiovascular Diseases（2022）

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摘要

•The obese group exhibited a more atherogenic lipid and carbohydrate metabolism.•Obese children and adolescents presented impaired cholesterol efflux.•The obese group displayed lower lecithin cholesterol acyl transferase activity.•Obese children and adolescents presented vascular specific inflammation.•The obese group displayed diminished aryl–esterase activity.

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关键词

Obesity,Children,Atherosclerosis,Lipoproteins,HDL functionality

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