Characteristics, Treatment and Outcome of 15 to 18 Years-Old Adolescents with Chronic Myeloid Leukemia (CML): The Experience of the International Registry of Childhood CML (I-CML-Ped Study)

Morgane Froment,Meinolf Suttorp,Stéphanie Ragot,Hélène Deutsch, Violaine Goyeau,Barbara De Moerloose, Silvia Regina Brandalise,Marina Borisevich,Petr Sedlacek,Adalet Meral Gunes,Birgitte Lausen, Antonio Molines Honrubia,Gordana Jakovljevic,Birgitta Versluys,Krzysztof Kalwak,Andrea Hraskova,Frederic Millot

Blood（2021）

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摘要

Introduction: CML is a rare disease in children and adolescents, accounting for 2-3% of leukemia cases in this population. Pediatric CML is more frequent in the 2 nd decade of life but data on adolescents are limited. Only response to treatment has been analyzed in few studies and seems to be poorer in this age cohort. The International Registry of Childhood Chronic Myeloid Leukemia gave us the opportunity to analyze the characteristics and outcome in a large cohort of adolescents.

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