ELN IMDS Flow Working Group Validation of the Monocyte Assay for Chronic Myelomonocytic Leukemia Diagnosis By Flow Cytometry

Orianne Wagner-Ballon,Peter Bettelheim,Jeroen Lauf,Frauke Bellos,Matteo G. Della Porta,Erica Travaglino,Dolores Subirá,Irene Nuevo,Sihem Tarfi,Theresia M. Westers,Ulrika Johansson,Katherina Psarra,Serafeim Karathanos,Sergio Matarraz,Enrique Colado, Monali Gupta,Robin M. Ireland,Wolfgang Kern,Arjan van de Loosdrecht

Blood（2021）

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摘要

This ELN multicenter study demonstrates the robustness of the monocyte assay with only limited variability of cMo percentages, validates the 94% cutoff value, confirms its high sensitivity and specificity in PB and finally, also confirms the possibility of its use in BM samples.

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关键词

chronic myelomonocytic leukemia,classical monocytes,flow cytometry,monocytes,myelodysplastic syndrome

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