Management of Donor-Specific Antibodies in Haploidentical Transplant: Multicenter Experience from the Spanish Group of Hematopoietic Transplant (GETH-TC)

Rebeca Bailen,Jose Luis Vicario,Beatriz Herruzo,Luisa Maria Guerra,Ana Vallés,Albert Esquirol,Marta Fonseca,Laura Solán,Irene Sanchez Vadillo,Leyre Bento,Ariadna Pérez Martínez,Anna Torrent,Joud Zanabili,Maria Calbacho,Raquel Alenda, Miguel Ángel Moreno,Beatriz Gago,Anabelle Chinea,Irene García-Cadenas,Francisco Boix-Giner

Blood（2021）

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摘要

Background. Donor specific antibodies (DSAs) are preformed IgG antibodies with specificity against HLA molecules not shared with the donor that can lead to graft failure (GF) in the setting of mismatched HSCT. The aim of this study is to report the experience of the Spanish Group of Hematopoietic Transplant (GETH-TC) in patients with DSAs undergoing haplo-HSCT.

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