Intensive serum urate lowering for erosive gout

Nicola Dalbeth,Anthony J Doyle,Karen Billington,Greg D Gamble,Paul Tan,Kieran Latto, Thrishila Parshu Ram,Ravi Narang,Rachel Murdoch,David Bursill,Borislav Mihov,Lisa K Stamp,Anne Horne

LANCET RHEUMATOLOGY（2022）

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摘要

Compared to a serum urate target of <0.30 mmoles/liter, more intensive serum urate lowering is difficult to achieve with an oral urate-lowering therapy. Intensive serum urate lowering leads to a high medication burden and does not improve bone erosion scores in patients with erosive gout.

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