Contribution of -1031T/C and -376G/A tumor necrosis factor alpha polymorphisms and haplotypes to preeclampsia risk in Tunisia (North Africa)

Nozha Raguema,Marwa Ben Ali Gannoun,Hedia Zitouni,Dhafer Ben Letaifa,Ondrej Seda,Touhami Mahjoub,Julie L Lavoie

Journal of Reproductive Immunology（2022）

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摘要

•The minor allele TNF-α -1031C polymorphism is associated with preeclampsia.•-1031C and -376A (CA) haplotype was associated with a higher incidence of preeclampsia.•The TG haplotype seems to be associated with a reduced prevalence of preeclampsia.

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BMI,DBP,SBP,SNP,IUGR,TNF-α,RFLP,MAF

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