Performance of specific morphologic features in distinguishing low-grade squamous intraepithelial lesions from high-grade squamous intraepithelial lesions in borderline cases: a College of American Pathologists Cytopathology Committee multiobserver study

Paul N Staats,Diane Davis Davey,Benjamin L Witt,Mohiedean Ghofrani,Chengquan Zhao,Leslie G Dodd,Kelly Goodrich,Mujtaba Husain,Daniel F I Kurtycz,Donna K Russell,Rulong Z Shen,Rhona J Souers,Z Laura Tabatabai,Barbara A Crothers

Journal of the American Society of Cytopathology（2022）

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摘要

•Some Pap tests show features intermediate between LSIL and HSIL with consequent poor reproducibility.•Review by 11 observers of 21 such slides confirmed poor reproducibility and identified only number of HSIL and ASC-H cells as statistically correlated with correct classification from among 11 variables.

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关键词

Gynecologic cytology,Pap test,Low-grade squamous intraepithelial lesion,High-grade squamous intraepithelial lesion,Interobserver reproducibility

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