Co-Occurrence of Chronic Mucocutaneous Candidiasis with Woolly Hair

SKIN APPENDAGE DISORDERS(2021)

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摘要
Chronic mucocutaneous candidiasis is an immunodeficiency state, inherited or acquired, characterized by recurrent and/or persistent candidiasis of skin, nails, and mucous membranes. Woolly hair is a congenital structural anomaly of scalp hair, characterized by light-colored, short, extremely kinky, and thin hair due to premature termination of anagen phase of hair cycle. Both conditions are known to present in syndromic and non-syndromic forms. We report the co-occurrence of both these conditions in a 10-year-old female child. The diagnosis was confirmed with clinical, trichoscopic, microbiologic, histopathologic, and laboratory evaluation, though mutational analysis could not be done due to resource constraints. The occurrence of both these diseases in the same individual has not been previously reported to the best of our knowledge. It could be a result of an association with ectodermal dysplasia.
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关键词
Chronic mucocutaneous candidiasis, Woolly hair, Trichoscopy
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