Enhanced Eryptosis in Glucose-6-Phosphate Dehydrogenase Deficiency.

Ghada Bouguerra, Khaoula Talbi,Nawel Trabelsi,Dorra Chaouachi,Imen Boudriga,Salem Abbès,Samia Menif

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology（2021）

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摘要

Our study uncovers a novel effect detected in G6PD-deficient erythrocytes which is cell membrane scrambling with PS translocation to the erythrocyte surface. Our findings shed a light on the mechanisms of premature erythrocyte clearance in G6PD deficiency.

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Eryptosis, Phosphatidylserine exposure, Anemia, G6PD deficiency, Oxidative stress

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