Characterization and use in neutralization assays of avian influenza codon-optimized H5 and H7 retroviral pseudotypes

Karen Delgadillo-Gutiérrez,Juan Arturo Castelán-Vega,Alicia Jiménez-Alberto, Mariana Del Carmen Fernández-Lizárraga,Gerardo Aparicio-Ozores,Gloria Paulina Monterrubio-López,Rosa María Ribas-Aparicio

Journal of Virological Methods（2022）

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摘要

•H5 and H7-pseudotypes: safe and specific alternative to serological tools.•Hemagglutinin pseudotypes as potential novel tools for quality control of influenza vaccines.•New approaches to subtype-specific detection of influenza H5 and H7 antibodies.

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关键词

Retroviral pseudotypes,Avian influenza,Hemagglutinin,Neutralization assay,Neutralizing antibodies,Veterinary vaccines

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