Insular Stimulation Produces Mental Clarity and Bliss

U Nencha, L Spinelli, S Vulliemoz, M Seeck,F Picard

ANNALS OF NEUROLOGY(2022)

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摘要
For the first time, an ecstatic aura has been evoked through the electrical stimulation of the dorsal anterior insula during presurgical invasive intracerebral monitoring in a patient who did not suffer from an ecstatic form of epilepsy. This case provides more evidence that the anterior insula is the major generator of such a mystical-type experience even in individuals with no underlying brain network changes related to a preexisting ecstatic epilepsy. ANN NEUROL 2021
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