Choosing drugs for UK COVID-19 treatment trials

Patrick F. Chinnery,Marion Bonnet, Alison Cave,Matthias P. Hofer, Alastair Lamb,Glenn A. McConkey, Nicholas Medcalf,Stephen P. Smith,Teresa Tsakok,Robert Watson, Steve Webster, Tao You

NATURE REVIEWS DRUG DISCOVERY（2021）

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摘要

In 2020, the UK government funded a portfolio of platform trials to develop new treatments for COVID-19. A key feature was the independent prioritization of candidate drugs with central coordination to prevent duplication, accelerating recruitment to deliver definitive trial results. A similar approach could be used for non-communicable diseases where treatment advances have been limited.

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