EIF1A depletion restrains human pituitary adenoma progression

Rongxin Geng,Xiaonan Zhu,Xiang Tao,Junhui Liu,Haitao Xu

Translational Oncology（2022）

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摘要

•EIF1A was upregulated in pituitary adenoma cells.•EIF1A knockdown repealed pro-tumor actions resulted from its overexpression.•Depleting EIF1A limited tumor growth in vivo.•Downregulation of MAPK9 was involved in the ANTXR1-mediated tumorigenesis.

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关键词

EIF1A,Pituitary adenoma,Cell proliferation,Cell migration,MAPK

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