Outcome without any adjuvant systemic treatment in stage I ER+/HER2− breast cancer patients included in the MINDACT trial

Annals of Oncology(2022)

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摘要
•Patients who received no AST had a 2.5% lower 8-year DMFI rate than that observed in matched patients who received ET.•Slightly more locoregional recurrences and contralateral breast cancers were observed in patients who received no AST.•These effects and side-effects of ET should be discussed with patients even at a very low risk of distant metastasis.
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关键词
low-risk breast cancer,no adjuvant systemic treatment,endocrine therapy,breast cancer recurrence
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