Memory and eating: A bidirectional relationship implicated in obesity

•Meal-related memory inhibits eating in humans.•Amnesia is associated with overeating and impaired interoception in humans.•Research in rodents and humans implicates the hippocampus in these effects.•Obesity disrupts memory and hippocampal functioning in rodents and humans.•These effects of obesity may create a vicious cycle that perpetuates obesity.