Glutathione S-Transferase Omega-2 and Transforming Growth Factor- β 1 Polymorphisms in Iranian Glaucoma Patients.

The presented results revealed that there was a significant association between the ND genotype of GSTO2 and the pathogenesis of glaucoma. Furthermore, this genotype can be considered as a sex-dependent genetic risk factor for the development of glaucoma. In contrast, the CT genotype of TGF-1 is suggested to be a protective genetic factor against the pathogenesis of glaucoma.