Elevated CD19+Siglec-10+ B cell levels are correlated with systemic lupus erythematosus disease activity

Bomiao Ju,Jing Wang,Lingfei Mo,Jing Huang,Zhiming Hao,Xiaohong Lv,Dan Pu,Lan He

International Immunopharmacology（2022）

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摘要

•The proportion of CD19+Siglec-10+B cells was elevated in SLE patients.•The increase of CD19+Siglec-10+B cells was correlated with SLEDAI and C3.•HCQ treatment significantly attenuated the proportion of CD19+Siglec-10+B cells.

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关键词

CD19+Siglec-10+ B cells,SLE,Disease severity,Hydroxychloroquine,Dexamethasone

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