Analysis of DUX4 Expression in Bone Marrow and Re-Discussion of DUX4 Function in the Health and Disease.

Ceren Hangul, Oznur Tokta,Sibel Berker Karauzum,Bahar Akkaya, Hulya Yildirim,Funda Tayfun Kupesiz, Ayse Nur Akinel

Turk patoloji dergisi（2022）

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摘要

With these results, novel expression for DUX4 in hematopoietic tissue is described. Further studies on the function of DUX4 in hematopoietic cells can shed light on DUX4-related pathways, and contribute to the treatment of DUX4-related diseases such as B-ALL, other cancers, and facioscapulohumeral muscular dystrophy.

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关键词

DUX4,Bone marrow,Hematopoietic progenitor cells,B-ALL,Cancer,Facioscapulohumeral muscular dystrophy

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