Prognostic factors in salvage surgery for recurrent head and neck cancer: A systematic review and meta-analysis

This systematic review and meta-analysis summarizes the association of pre-surgery and postsurgery factors with poor overall survival or progression free-survival (significant pooled hazard ratios were reported in red) in patients undergoing salvage surgery for recurrent head and neck cancer. The identification of pre-surgery factors associated with poor outcomes may help clinicians in the selection of the best candidate to salvage surgery, whereas post-surgery factors may help to tailor post-surgery surveillance.