Conditional gene targeting using UCP1-Cre mice directly targets the central nervous system beyond thermogenic adipose tissues

Kristin E Claflin,Kyle H Flippo,Andrew I Sullivan,Meghan C Naber,Bolu Zhou, Tate J Neff,Sharon O Jensen-Cody,Matthew J Potthoff

Molecular Metabolism（2022）

引用 12|浏览6

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摘要

•UCP1-Cre transgenic mice express Cre in tissues beyond thermogenic adipose tissues.•UCP1-Cre; tdTomato reporter mice show that Cre is also expressed throughout the brain, kidney, and adrenal glands.•Ucp1 mRNA is actively expressed in the central nervous system of adult mice.

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关键词

Adipose,Brain,VMH,Brown adipose tissue,Brown,Beige

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