Epitranscriptomic Analysis of N6-methyladenosine in Infant Rhesus Macaques after Multiple Sevoflurane Anesthesia

Neuroscience(2022)

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摘要
•Neonatal sevoflurane exposure induced the dynamic regulation of m6A in macaques.•After sevoflurane treatment, the macaques had more m6A peaks.•Hypermethylated genes were enriched in the regulation of synaptic plasticity.
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关键词
CC,DEGs,FDA,GO,KEGG,m6A,MeRIP-Seq,MF,YTHDF1,YTHDF3,BP
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