IL-17A and IFN-γ are Up-regulated in CD4 and γδ T Cells in Active Behcet's Disease Patients

Immunology Letters(2022)

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摘要
•IFN-γ, IL-17A and IL-22 related to γδ T cells are evaluated in Behçet's disease (BD)•Functional states of both CD4+ and γδ T cells are compared in ex vivo samples•Only IFN-γ production was increased in γδ T cells of active BD patients•IL-17A and IL-17A/IFN-γ double producer CD4+ T cells were increased in active BD•Along with CD4+ T cells, γδ T cells have complementary roles in BD
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关键词
Behçet's disease,γδ T cell,T helper cells,IL-17, IFN-γ
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