Evaluation of the Determination of Dabigatran, Rivaroxaban, and Apixaban in Lupus Anticoagulant-Positive Patients.

Jana Úlehlová,Barbora Piskláková,Eliška Ivanovová,Jana Procházková,Pavla Bradáčová,Aleš Kvasnička,David Friedecký,Luděk Slavík

Diagnostics (Basel, Switzerland)（2021）

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摘要

The acute findings of the presence of LA-type antibodies fundamentally affects the determination of DOAC by functional tests, and in this case, it is necessary to use LC-MS analysis to determine the true value. If patients treated with DOAC develop LA of medium and higher titers, we do not recommend checking DOAC levels with functional tests.

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关键词

DOAC-Stop,apixaban,dabigatran,liquid chromatography tandem mass spectrometry,rivaroxaban

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