Biosensor-based isolation of amino acid-producing Vibrio natriegens strains

Roberto Giuseppe Stella, Philipp Baumann, Sophia Lorke, Felix Münstermann,Astrid Wirtz,Johanna Wiechert,Jan Marienhagen,Julia Frunzke

Metabolic Engineering Communications(2021)

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摘要
The marine bacterium Vibrio natriegens has recently been demonstrated to be a promising new host for molecular biology and next generation bioprocesses. V. natriegens is a Gram-negative, non-pathogenic slight-halophilic bacterium, with a high nutrient versatility and a reported doubling time of under 10 min. However, V. natriegens is not an established model organism yet, and further research is required to promote its transformation into a microbial workhorse.
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关键词
Transcription factor-based biosensors,Metabolic engineering,Amino acid production,High-throughput screening
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