Extramedullary acute myeloid leukemia (eAML): Retrospective single center cohort study on clinico-pathological, molecular analysis and survival outcomes

•eAML is a rare entity and occurs at a younger in Jordan.•It requires advanced methods for the diagnosis, and identification of targetable mutations, that may dictate therapeutic approaches.•AML-like induction chemotherapy regimens remain the standard of care, and consolidation therapy is controversial.•Failure to achieve complete remission is associated with worse survival outcomes.•Allogeneic hematopoietic transplant may be considered in first complete remission.•Post-transplant relapses are common and responsible for increased mortality and shorter survival.