Chemoenzymatic synthesis of fucosylated oligosaccharides using Thermosynechococcus α1–2-fucosyltransferase and their application in the regulation of intestinal microbiota

Food Chemistry: X(2021)

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摘要
•A novel α1,2-fucosyltransferase was cloned from Thermosynechococcus.•Tsα1,2-FT catalyzes one-pot multi-enzyme synthesis of lacto-N-fucopentaose-I.•LNFP-I was verified to promote the growth of intestinal probiotics.
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关键词
Carbohydrate,Enzymatic synthesis,Fucosyltransferase,Fucosylated oligosaccharides,Lacto-N-fucopentaose I,Thermosynechococcus
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