Inflammatory Bowel Disease Risk Variants Are Associated With An Increased Risk Of Skin Cancer

Kelly Cushing,Xiaomeng Du,Yanhua Chen,L. C. Stetson,Annapurna Kuppa,Vincent L. Chen,J. Michelle Kahlenberg,Johann Gudjonsson,Peter D. Higgins,Elizabeth Speliotes

GASTROENTEROLOGY（2021）

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摘要

The results of this study highlight shared genetic susceptibility across IBD and skin cancer, with increased risk of NMSC in those who carry risk variants in IRF4, PTPN22, CPEB4, and BACH2 and increased risk of MSC in those who carry a risk variant in IL2RA.

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genetics,inflammatory bowel disease,skin cancer

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