Diastereoselective Synthesis of oxa‐Bridged Tetracyclic Benzooxazines from the Reaction of 2‐Isocyanophenyloxyacrylates and Propargylic Esters
Advanced Synthesis and Catalysis（2021）
摘要
A cascade annulation of 2‐isocyanophenyloxyacrylate and propargylic ester under basic conditions has been disclosed. This methodology enables diastereoselective synthesis of oxa‐bridged tetracyclic benzooxazine. The annulation proceeds through isomerization, Michael addition, triple annulation and acyl migration processes.
更多查看译文
关键词
2-Isocyanophenyloxyacrylate,Propargylic ester,Diastereoselective synthesis,Tetracyclic benzooxazine
AI 理解论文
溯源树
样例
生成溯源树，研究论文发展脉络
Chat Paper
正在生成论文摘要