Pythiosis in Equidae in Northeastern Brazil: 1985–2020

•Pythiosis is a chronic inflammatory disease caused by the oomycete Pythium insidiosum;•The disease was diagnosed in 195 horses, six mules and one donkey;•Lesions were preferentially located on the limbs and ventral thoracoabdominal wall;•The intralesional kunkers establishes an accurate presumptive diagnosis.