Vitamin B12 Deficiency Manifesting As Reversible Leukoencephalopathy And Ataxia

Neha Kapoor,Jasmine Parihar,Deepa Dash,Manjari Tripathi,Rohit Bhatia,Ajay Garg,Rajesh Kumar Singh

NEUROLOGY ASIA（2021）

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摘要

We present here a 52 years old man with rapidly progressive cognitive decline and ataxia. Brain MRI showed confluent white matter changes and spinal MRI showed posterior column changes. The patient had vitamin B12 deficiency from pernicious anemia. There was clinical and radiological improvement by vitamin B12 replacement. There is no previous report of pernicious anemia causing reversible leukoencephalopathy and ataxia.

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关键词

Vitamin B12, pernicious anemia, leukoencephalopathy, ataxia, white matter changes, SACD

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