Double enhancement of immunogenic cell death and antigen presentation for cancer immunotherapy

Xiang Xiong,Jingya Zhao,Rui Su,Chunping Liu,Xing Guo,Shaobing Zhou

Nano Today（2021）

引用 39|浏览4

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摘要

•A tumor immunotherapy strategy was developed by the combination of biomimetic nanoparticles and in situ formed hydrogel.•The biomimetic nanoparticle was capable of inducing immunogenic cell death of tumor cells.•The alginate gel locally released XCL-1 to recruit regular DC cells into the tumor tissue.

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关键词

Biomimetic nanoparticles,Immunogenic cell death,Chemotaxis,Cross-presentation,Immunotherapy

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