Genetic Variations Of Cyp450 And Abc Transporters Associated With Trabectedin Severe Hepatotoxicity In Patients With Advanced Soft--Tissue Sarcoma: A Pharmacogenetic Study

M. Maillard,C. Chevreau,F. Le Louedec, M. Cassou, C. Delmas, L. Gourdain,J. Y. Blay, D. Cupissol, E. Bompas, A. Italiano,N. Isambert, C. Delcambre-Lair, N. Penel, F. Bertucci, C. Guillemet, J. Plenecassagnes, S. Foulon, E. Chatelut,A. Le Cesne, F. Thomas

FUNDAMENTAL & CLINICAL PHARMACOLOGY（2021）

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关键词

ABC transporters, advanced soft-tissue sarcoma, CYP450, hepatotoxicity, next-generation sequencing, pharmacogenetic, trabectedin

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