Free Radicals In Mycobacterial Disease

This chapter will discuss the role of the well-defined free radicals nitric oxide and superoxide in the context of mycobacterial disease and experimental animal models in order to summarize their essential roles in inflammation and immunity. Research articles and reviews will be discussed based on their citation index and placed within the context of immunity to mycobacterial disease in humans and experimental animal models. The final portion of this chapter will be devoted to descriptions of some of the assays used to define the roles and sources of these free radicals within the context of mycobacterial disease.