Thionation Of The 2-Lambda(5)-Phosphaquinolin-2-One Scaffold With Lawesson'S Reagent

Lawesson's reagent is one of the most common thionating reagents that has found use for several decades on a variety of carbonyl systems. Herein, we report the transformation of the 2-lambda(5)-phosphaquinolin-2-one structure to its respective 2-lambda(5)-phosphaquinolin-2-thione derivative. Solution-state characterization of both P-OPh and P-Ph thio analogues, as well as solid-state structures for the latter system, are reported.