Extract of radish (R. Sativus Linn) promotes anti-atherosclerotic effect using urine metabolomics in ApoE−/− mice

•Radish extracts improve vascular plaque and plasma lipid profile.•Radish extracts reduced inflammatory mRNA expression and metabolites.•Nitric oxide related mRNA expression and metabolite are regulated by radish extracts.•Trend of intensities of steroid-hormones in urine are matched to plasma lipids.