Seizure control after late introduction of anakinra in a patient with adult onset Rasmussen’s encephalitis

•Ten percentage of patient with RE has adult onset of symptoms.•Experience with IL-1Ra like anakinra in RE patients is limited.•26 years after RE onset anakinra was introduced and led to complete seizure control.•Premature withdrawal of anakinra (2 months) caused relapse of seizures.•Our patient remains seizure free 13 months after 2nd course (7 months) of anakinra.