Synthesis And Monoamine Transporter Affinity Of 3 Beta-(4-(2-Pyrrolyl)Phenyl)-8-Azabicyclo[3.2.1]Octanes And 3 Beta-(5-Indolyl)-8-Azabicyclo[3.2.1]Octanes

Hml Davies, Pd Ren, N Kong,T Sexton,Sr Childers

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS（2001）

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摘要

3 beta-(5-Indolyl)-8-azabicyclo[3.2.1]octanes display potent binding affinity for both the dopamine and serotonin transporters, while certain 3 beta-(4-(2-pyrrolyl)phenyl)-8-azabicyclo[3.2.1]octanes selectively bind to the serotonin transporter. (C) 2001 Elsevier Science Ltd. All rights reserved.

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