Corticosteroid Therapy Of Flares In Ulcerative Colitis Is Less Effective In Patients With Prior Biologic Therapy

Background and aims Corticosteroids are still widely used to treat flares of ulcerative colitis (UC) but steroid-refractory UC has been reported in 24-33 % of patients in historic cohorts. This study aimed to assess factors influencing efficacy of corticosteroid therapy for active UC in the biologic era.