Nickel-Catalyzed Deaminative Cross-Coupling Of Disulfides With Katritzky Pryidium Salts To Construct Sulfides

The synthesis of thioether or selenoether through the cross-coupling of C-S or C-Se bond is a high attractive research area due to the prevalence of thioether or selenoether in pharmaceutically active compounds, bioactive natural compounds, agrochemicals, and functional materials. Herein, a novel and general method has been developed for the construction of C-S or C-Se bonds using Katritzky pyridinium salts with disulfides or diselenides in the presence of nickel catalyst. This procedure exhibits remarkable functional group tolerance. Under mild reaction condition, a variety of thioethers and selenoethers is successfully and efficiently obtained through deaminative cross-coupling.